Saturday, October 18, 2008

Vitamin D and some of the mercury studies

Recently Vitamin D deficiency has been connected to autism. Nobody gave a reason for why there might be a connection. My contention is that the reason why people with autism might have vitamin D deficiency is not only because autistics often have intestinal absorption problems but also because mercury attacks the kidney in the place where the Vitamin D hormone 1,25 dihydroxy cholecalciferol (calcitriol) is made. That place would be the kidney's proximal tubule.

I learned of another reason that connects mercury and Vitamin D to autism. It turns out Vitamin D is necessary for making glutathione and glutathione is all important for the mercury detoxification process. Autistic kids can't detoxify well enough to prevent autism. Who would have thought? So here we have a double whammy. There is not enough calcitriol being made because mercury destroys the kidney and for that reason there is not enough glutathione made to detoxify mercury.

Any comments? Please!

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And here is more: I read Dr. Jane Hightower's book "Diagnosis: Mercury". It is a well-written book and gives a great account about the conflicts of interest that surround the mercury debate. A must read! It gives lots of insight into the politics of mercury.

As I was reading the book it occurred to me that the reason why the Seychelles and Faroe studies show such divergent outcomes. The Seychelles children had no ill effects from eating mercury-laden fish, the Faroe Island children did. One might be able to explain the discrepancy by relating it to the abundance of Vitamin D in the Seychelles and the relative lack of it in the Faroe Islands. The Faroe Islands are at a latitude where Vitamin D deficiency is very likely even with high fish consumption. The Seychelles are close to the equator. That makes children who live there much better able to make Vitamin D and with that more glutathione for better detoxification.

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